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Efficient CRISPR-Cas9–mediated genome editing in Plasmodium falciparum

Efficient CRISPR-Cas9–mediated genome editing in Plasmodium falciparum

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1668251401

Efficient CRISPR-Cas9–mediated genome editing in Plasmodium falciparum

About this item

Full title

Efficient CRISPR-Cas9–mediated genome editing in Plasmodium falciparum

Publisher

New York: Nature Publishing Group US

Journal title

Nature methods, 2014-09, Vol.11 (9), p.915-918

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Single guide RNAs driven by a
T7
promoter target Cas9 to two endogenous loci, leading to fast and efficient genome editing in the malaria parasite
P. falciparum.
Malaria is a major cause of global morbidity and mortality, and new strategies for treating and preventing this disease are needed. Here we show that the
Streptococcus pyoge...

Alternative Titles

Full title

Efficient CRISPR-Cas9–mediated genome editing in Plasmodium falciparum

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1668251401

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1668251401

Other Identifiers

ISSN

1548-7091

E-ISSN

1548-7105

DOI

10.1038/nmeth.3063

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