Immunohistochemistry is highly sensitive and specific for the detection of NRASQ61R mutation in mela...
Immunohistochemistry is highly sensitive and specific for the detection of NRASQ61R mutation in melanoma
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
Testing for
NRAS
is now integral part in the assessment of metastatic melanoma patients because there is evidence that
NRAS
-mutated patients may be sensitive to MEK inhibitors, and
RAS
mutation is a common mechanism of acquired resistance during treatment with BRAF inhibitors. This study evaluated the sensitivity and specificity...
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Full title
Immunohistochemistry is highly sensitive and specific for the detection of NRASQ61R mutation in melanoma
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Record Identifier
TN_cdi_proquest_miscellaneous_1669832745
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1669832745
Other Identifiers
ISSN
0893-3952
E-ISSN
1530-0285
DOI
10.1038/modpathol.2014.137
