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System L amino acid transporter LAT1 accumulates O-(2-fluoroethyl)-L-tyrosine (FET)

System L amino acid transporter LAT1 accumulates O-(2-fluoroethyl)-L-tyrosine (FET)

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1669857547

System L amino acid transporter LAT1 accumulates O-(2-fluoroethyl)-L-tyrosine (FET)

About this item

Full title

System L amino acid transporter LAT1 accumulates O-(2-fluoroethyl)-L-tyrosine (FET)

Publisher

Vienna: Springer-Verlag

Journal title

Amino acids, 2015-02, Vol.47 (2), p.335-344

Language

English

Formats

Publication information

Publisher

Vienna: Springer-Verlag

More information

Scope and Contents

Contents

O-(2-fluoroethyl)-L-tyrosine (FET) labeled with fluorine-18 is an important and specific tracer for diagnostics of glioblastoma via positron emission tomography (PET). However, the mechanism of its quite specific accumulation in tumor tissue has not been understood so far. In this work we demonstrate that [³H]L-tyrosine is primarily transported by...

Alternative Titles

Full title

System L amino acid transporter LAT1 accumulates O-(2-fluoroethyl)-L-tyrosine (FET)

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1669857547

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1669857547

Other Identifiers

ISSN

0939-4451

E-ISSN

1438-2199

DOI

10.1007/s00726-014-1863-3

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