Therapeutic antibody targeting of individual Notch receptors
Therapeutic antibody targeting of individual Notch receptors
About this item
Full title
Author / Creator
Wu, Yan , Cain-Hom, Carol , Choy, Lisa , Hagenbeek, Thijs J. , de Leon, Gladys P. , Chen, Yongmei , Finkle, David , Venook, Rayna , Wu, Xiumin , Ridgway, John , Schahin-Reed, Dorreyah , Dow, Graham J. , Shelton, Amy , Stawicki, Scott , Watts, Ryan J. , Zhang, Jeff , Choy, Robert , Howard, Peter , Kadyk, Lisa , Yan, Minhong , Zha, Jiping , Callahan, Christopher A. , Hymowitz, Sarah G. and Siebel, Christian W.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Direct action: antitumour potential of Notch receptor antagonists
The four receptors of the Notch family are widely expressed transmembrane proteins through which mammalian cells communicate to regulate cell fate and growth. Defects in Notch signalling are linked to many cancers, including acute lymphoblastic leukaemia. Using phage display techn...
Alternative Titles
Full title
Therapeutic antibody targeting of individual Notch receptors
Authors, Artists and Contributors
Author / Creator
Cain-Hom, Carol
Choy, Lisa
Hagenbeek, Thijs J.
de Leon, Gladys P.
Chen, Yongmei
Finkle, David
Venook, Rayna
Wu, Xiumin
Ridgway, John
Schahin-Reed, Dorreyah
Dow, Graham J.
Shelton, Amy
Stawicki, Scott
Watts, Ryan J.
Zhang, Jeff
Choy, Robert
Howard, Peter
Kadyk, Lisa
Yan, Minhong
Zha, Jiping
Callahan, Christopher A.
Hymowitz, Sarah G.
Siebel, Christian W.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1671339788
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1671339788
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature08878
