Covert warfare against the immune system: decoy capsids, stealth genomes, and suppressors
Covert warfare against the immune system: decoy capsids, stealth genomes, and suppressors
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United States: Elsevier Limited
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English
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United States: Elsevier Limited
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Contents
In part owing to their low immune profile, adeno-associated virus (AAV) vectors have long been viewed as ideal for in vivo gene transfer. They are based on a small, nonpathogenic virus that is composed of a single-stranded DNA genome and a protein capsid. As compared with many other viral vectors, recombinant AAVs are better at avoiding activation...
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Covert warfare against the immune system: decoy capsids, stealth genomes, and suppressors
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TN_cdi_proquest_miscellaneous_1673399788
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1673399788
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ISSN
1525-0016
E-ISSN
1525-0024
DOI
10.1038/mt.2013.176