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underlying mechanism for the increased mutagenesis of lagging-strand genes in Bacillus subtilis

underlying mechanism for the increased mutagenesis of lagging-strand genes in Bacillus subtilis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1676349482

underlying mechanism for the increased mutagenesis of lagging-strand genes in Bacillus subtilis

About this item

Full title

underlying mechanism for the increased mutagenesis of lagging-strand genes in Bacillus subtilis

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2015-03, Vol.112 (10), p.E1096-E1105

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

We previously reported that lagging-strand genes accumulate mutations faster than those encoded on the leading strand in Bacillus subtilis . Although we proposed that orientation-specific encounters between replication and transcription underlie this phenomenon, the mechanism leading to the increased mutagenesis of lagging-strand genes remained unk...

Alternative Titles

Full title

underlying mechanism for the increased mutagenesis of lagging-strand genes in Bacillus subtilis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1676349482

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1676349482

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1416651112

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