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Mutual antagonism between Sox10 and NFIA regulates diversification of glial lineages and glioma subt...

Mutual antagonism between Sox10 and NFIA regulates diversification of glial lineages and glioma subt...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1676351439

Mutual antagonism between Sox10 and NFIA regulates diversification of glial lineages and glioma subtypes

About this item

Full title

Mutual antagonism between Sox10 and NFIA regulates diversification of glial lineages and glioma subtypes

Publisher

New York: Nature Publishing Group US

Journal title

Nature neuroscience, 2014-10, Vol.17 (10), p.1322-1329

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Sox10 and Nuclear Factor I-A (NFIA) are transcriptional regulators of oligodendrocyte and astrocyte generation in the mammalian brain, respectively. This study describes reciprocal antagonism between these transcription factors whereby NFIA directly antagonizes Sox10 regulation of myelin gene expression in oligodendrocytes, and Sox10 negatively reg...

Alternative Titles

Full title

Mutual antagonism between Sox10 and NFIA regulates diversification of glial lineages and glioma subtypes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1676351439

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1676351439

Other Identifiers

ISSN

1097-6256

E-ISSN

1546-1726

DOI

10.1038/nn.3790

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