Germinal centres and B cell lymphomagenesis
Germinal centres and B cell lymphomagenesis
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Key Points
The germinal centre (GC) is the histological structure dedicated to the generation and selection of B cells that produce high-affinity antibodies. It also represents the site from which most B cell lymphomas originate.
The GC is functionally polarized — the dark zone is the site of B cell divisions and immunoglobulin somatic hyperm...
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Germinal centres and B cell lymphomagenesis
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TN_cdi_proquest_miscellaneous_1676363417
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1676363417
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ISSN
1474-1733
E-ISSN
1474-1741
DOI
10.1038/nri3814