dDsk2 regulates H2Bub1 and RNA polymerase II pausing at dHP1c complex target genes
dDsk2 regulates H2Bub1 and RNA polymerase II pausing at dHP1c complex target genes
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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dDsk2 is a conserved extraproteasomal ubiquitin receptor that targets ubiquitylated proteins for degradation. Here we report that dDsk2 plays a nonproteolytic function in transcription regulation. dDsk2 interacts with the dHP1c complex, localizes at promoters of developmental genes and is required for transcription. Through the ubiquitin-binding do...
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dDsk2 regulates H2Bub1 and RNA polymerase II pausing at dHP1c complex target genes
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TN_cdi_proquest_miscellaneous_1677886859
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1677886859
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E-ISSN
2041-1723
DOI
10.1038/ncomms8049
