SIRT3 deficiency impairs mitochondrial and contractile function in the heart
SIRT3 deficiency impairs mitochondrial and contractile function in the heart
About this item
Full title
Author / Creator
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
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Publication information
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Subjects
More information
Scope and Contents
Contents
Sirtuin 3 (SIRT3) is a mitochondrial NAD
+
-dependent deacetylase that regulates energy metabolic enzymes by reversible protein lysine acetylation in various extracardiac tissues. The role of SIRT3 in myocardial energetics and in the development of mitochondrial dysfunction in cardiac pathologies, such as the failing heart, remains to be eluc...
Alternative Titles
Full title
SIRT3 deficiency impairs mitochondrial and contractile function in the heart
Authors, Artists and Contributors
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Record Identifier
TN_cdi_proquest_miscellaneous_1680751956
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1680751956
Other Identifiers
ISSN
0300-8428
E-ISSN
1435-1803
DOI
10.1007/s00395-015-0493-6
