MAPK inhibitors differently modulate TGF-β/Smad signaling in HepG2 cells
MAPK inhibitors differently modulate TGF-β/Smad signaling in HepG2 cells
About this item
Full title
Publisher
Dordrecht: Springer Netherlands
Journal title
Language
English
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Publication information
Publisher
Dordrecht: Springer Netherlands
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More information
Scope and Contents
Contents
The aim of this study was to investigate the mitogen-activated protein kinase (MAPK) pathway, which crosstalk with TGF-β/Smad signaling via linker phosphorylation of Smad2/3 to promote hepatocarcinogenesis. After DEN-induced hepatocellular carcinoma (HCC) in rats showed increased phosphorylation of JNK1/2, p38, and ERK1/2, we next antagonized TGF-β...
Alternative Titles
Full title
MAPK inhibitors differently modulate TGF-β/Smad signaling in HepG2 cells
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1683756119
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1683756119
Other Identifiers
ISSN
1010-4283
E-ISSN
1423-0380
DOI
10.1007/s13277-014-3002-x
