Independent genomewide screens identify the tumor suppressor VTRNA2-1 as a human epiallele responsiv...
Independent genomewide screens identify the tumor suppressor VTRNA2-1 as a human epiallele responsive to periconceptional environment
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Author / Creator
Silver, Matt J , Kessler, Noah J , Hennig, Branwen J , Dominguez-Salas, Paula , Laritsky, Eleonora , Baker, Maria S , Coarfa, Cristian , Hernandez-Vargas, Hector , Castelino, Jovita M , Routledge, Michael N , Gong, Yun Yun , Herceg, Zdenko , Lee, Yong Sun , Lee, Kwanbok , Moore, Sophie E , Fulford, Anthony J , Prentice, Andrew M and Waterland, Robert A
Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publication information
Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Interindividual epigenetic variation that occurs systemically must be established prior to gastrulation in the very early embryo and, because it is systemic, can be assessed in easily biopsiable tissues. We employ two independent genome-wide approaches to search for such variants.
First, we screen for metastable epialleles by performing genomewi...
Alternative Titles
Full title
Independent genomewide screens identify the tumor suppressor VTRNA2-1 as a human epiallele responsive to periconceptional environment
Authors, Artists and Contributors
Author / Creator
Kessler, Noah J
Hennig, Branwen J
Dominguez-Salas, Paula
Laritsky, Eleonora
Baker, Maria S
Coarfa, Cristian
Hernandez-Vargas, Hector
Castelino, Jovita M
Routledge, Michael N
Gong, Yun Yun
Herceg, Zdenko
Lee, Yong Sun
Lee, Kwanbok
Moore, Sophie E
Fulford, Anthony J
Prentice, Andrew M
Waterland, Robert A
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1687997783
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1687997783
Other Identifiers
ISSN
1474-7596
E-ISSN
1474-760X
DOI
10.1186/s13059-015-0660-y
