Association between edoxaban dose, concentration, anti-Factor Xa activity, and outcomes: an analysis...
Association between edoxaban dose, concentration, anti-Factor Xa activity, and outcomes: an analysis of data from the randomised, double-blind ENGAGE AF-TIMI 48 trial
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Author / Creator
Ruff, Christian T, Dr , Giugliano, Robert P, MD , Braunwald, Eugene, Prof , Morrow, David A, MD , Murphy, Sabina A, MPH , Kuder, Julia F, MA , Deenadayalu, Naveen, MPH , Jarolim, Petr, MD , Betcher, Joshua, PhD , Shi, Minggao, PhD , Brown, Karen, PhD , Patel, Indravadan, MD , Mercuri, Michele, MD and Antman, Elliott M, Prof
Publisher
England: Elsevier Ltd
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Language
English
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Publisher
England: Elsevier Ltd
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Contents
Summary Background New oral anticoagulants for stroke prevention in atrial fibrillation were developed to be given in fixed doses without the need for the routine monitoring that has hindered usage and acceptance of vitamin K antagonists. A concern has emerged, however, that measurement of drug concentration or anticoagulant activity might be neede...
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Full title
Association between edoxaban dose, concentration, anti-Factor Xa activity, and outcomes: an analysis of data from the randomised, double-blind ENGAGE AF-TIMI 48 trial
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TN_cdi_proquest_miscellaneous_1690210919
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1690210919
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ISSN
0140-6736
E-ISSN
1474-547X
DOI
10.1016/S0140-6736(14)61943-7
