High OCT4 and Low p16^(INK4A) Expressions Determine In Vitro Lifespan of Mesenchymal Stem Cells
High OCT4 and Low p16^(INK4A) Expressions Determine In Vitro Lifespan of Mesenchymal Stem Cells
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Publisher
United States: Hindawi Limiteds
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Language
English
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Publisher
United States: Hindawi Limiteds
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After long-term culture, mesenchymal stem cells alter their biological properties and enter into a state of replicative senescence. Although several classical biomarkers have been used for quantitative assessment of cellular senescence, no hallmark has been proven completely unique to the senescent state in cells. We used bone marrow-derived MSCs (...
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Full title
High OCT4 and Low p16^(INK4A) Expressions Determine In Vitro Lifespan of Mesenchymal Stem Cells
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TN_cdi_proquest_miscellaneous_1690215110
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1690215110
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ISSN
1687-966X
DOI
10.1155/2015/369828
