Ku-Mediated Coupling of DNA Cleavage and Repair during Programmed Genome Rearrangements in the Cilia...
Ku-Mediated Coupling of DNA Cleavage and Repair during Programmed Genome Rearrangements in the Ciliate Paramecium tetraurelia: e1004552
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San Francisco: Public Library of Science
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Language
English
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Publisher
San Francisco: Public Library of Science
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Contents
During somatic differentiation, physiological DNA double-strand breaks (DSB) can drive programmed genome rearrangements (PGR), during which DSB repair pathways are mobilized to safeguard genome integrity. Because of their unique nuclear dimorphism, ciliates are powerful unicellular eukaryotic models to study the mechanisms involved in PGR. At each...
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Full title
Ku-Mediated Coupling of DNA Cleavage and Repair during Programmed Genome Rearrangements in the Ciliate Paramecium tetraurelia: e1004552
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TN_cdi_proquest_miscellaneous_1691281095
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1691281095
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ISSN
1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1004552
