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Mitochondrial dysfunction and respiratory chain defects in a rodent model of methotrexate-induced en...

Mitochondrial dysfunction and respiratory chain defects in a rodent model of methotrexate-induced en...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1691293092

Mitochondrial dysfunction and respiratory chain defects in a rodent model of methotrexate-induced enteritis

About this item

Full title

Mitochondrial dysfunction and respiratory chain defects in a rodent model of methotrexate-induced enteritis

Publisher

London, England: SAGE Publications

Journal title

Human & experimental toxicology, 2014-10, Vol.33 (10), p.1051-1065

Language

English

Formats

Publication information

Publisher

London, England: SAGE Publications

More information

Scope and Contents

Contents

The efficacy of methotrexate (MTX), a widely used chemotherapeutic drug, is limited by its gastrointestinal toxicity and the mechanism of which is not clear. The present study investigates the possible role of mitochondrial damage in MTX-induced enteritis. Small intestinal injury was induced in Wistar rats by the administration of 7 mg kg−1 body wt...

Alternative Titles

Full title

Mitochondrial dysfunction and respiratory chain defects in a rodent model of methotrexate-induced enteritis

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1691293092

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1691293092

Other Identifiers

ISSN

0960-3271

E-ISSN

1477-0903

DOI

10.1177/0960327113515503

How to access this item