Mitochondrial dysfunction and respiratory chain defects in a rodent model of methotrexate-induced en...
Mitochondrial dysfunction and respiratory chain defects in a rodent model of methotrexate-induced enteritis
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Author / Creator
Kolli, VK , Natarajan, K , Isaac, B , Selvakumar, D and Abraham, P
Publisher
London, England: SAGE Publications
Journal title
Language
English
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Publisher
London, England: SAGE Publications
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Scope and Contents
Contents
The efficacy of methotrexate (MTX), a widely used chemotherapeutic drug, is limited by its gastrointestinal toxicity and the mechanism of which is not clear. The present study investigates the possible role of mitochondrial damage in MTX-induced enteritis. Small intestinal injury was induced in Wistar rats by the administration of 7 mg kg−1 body wt...
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Full title
Mitochondrial dysfunction and respiratory chain defects in a rodent model of methotrexate-induced enteritis
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Record Identifier
TN_cdi_proquest_miscellaneous_1691293092
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1691293092
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ISSN
0960-3271
E-ISSN
1477-0903
DOI
10.1177/0960327113515503