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Lack of hyaluronidases exacerbates renal post-ischemic injury, inflammation, and fibrosis

Lack of hyaluronidases exacerbates renal post-ischemic injury, inflammation, and fibrosis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1693186980

Lack of hyaluronidases exacerbates renal post-ischemic injury, inflammation, and fibrosis

About this item

Full title

Lack of hyaluronidases exacerbates renal post-ischemic injury, inflammation, and fibrosis

Publisher

United States: Elsevier Inc

Journal title

Kidney international, 2015-07, Vol.88 (1), p.61-71

Language

English

Formats

Publication information

Publisher

United States: Elsevier Inc

More information

Scope and Contents

Contents

Renal ischemia–reperfusion injury (IRI) is a pathological process that may lead to acute renal failure and chronic dysfunction in renal allografts. During IRI, hyaluronan (HA) accumulates in the kidney, but suppression of HA accumulation during IRI protects the kidney from ischemic insults. Here we tested whether Hyal1−/− and Hyal2−/− mice display...

Alternative Titles

Full title

Lack of hyaluronidases exacerbates renal post-ischemic injury, inflammation, and fibrosis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1693186980

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1693186980

Other Identifiers

ISSN

0085-2538

E-ISSN

1523-1755

DOI

10.1038/ki.2015.53

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