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A distinct mechanism for activating uncoupled nicotinic acetylcholine receptors

A distinct mechanism for activating uncoupled nicotinic acetylcholine receptors

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1694972333

A distinct mechanism for activating uncoupled nicotinic acetylcholine receptors

About this item

Full title

A distinct mechanism for activating uncoupled nicotinic acetylcholine receptors

Publisher

New York: Nature Publishing Group US

Journal title

Nature chemical biology, 2013-11, Vol.9 (11), p.701-707

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Membrane hydrophobic thickness modulates transitions between uncoupled and coupled nAChRs by a kinetic mechanism.
The ability of the nicotinic acetylcholine receptor (nAChR) to undergo conformational transitions is exquisitely sensitive to its surrounding lipid environment. Previous work has highlighted a conformational selection mechanism, wher...

Alternative Titles

Full title

A distinct mechanism for activating uncoupled nicotinic acetylcholine receptors

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1694972333

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1694972333

Other Identifiers

ISSN

1552-4450

E-ISSN

1552-4469

DOI

10.1038/nchembio.1338

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