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Leptin reverses diabetes by suppression of the hypothalamic-pituitary-adrenal axis

Leptin reverses diabetes by suppression of the hypothalamic-pituitary-adrenal axis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1694972752

Leptin reverses diabetes by suppression of the hypothalamic-pituitary-adrenal axis

About this item

Full title

Leptin reverses diabetes by suppression of the hypothalamic-pituitary-adrenal axis

Publisher

New York: Nature Publishing Group US

Journal title

Nature medicine, 2014-07, Vol.20 (7), p.759-763

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Treatment with exogenous leptin has been reported to improve hyperglycemia in mouse models of type 1 diabetes through lowering of glucagon signaling. Jerry Shulman and his colleagues now report that the more primary beneficial effect of leptin on hyperglycemia is by reducing the activity of the hypothalamic-pituitary-adrenal axis. These results giv...

Alternative Titles

Full title

Leptin reverses diabetes by suppression of the hypothalamic-pituitary-adrenal axis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1694972752

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1694972752

Other Identifiers

ISSN

1078-8956

E-ISSN

1546-170X

DOI

10.1038/nm.3579

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