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Multiple functional variants in long-range enhancer elements contribute to the risk of SNP rs965513...

Multiple functional variants in long-range enhancer elements contribute to the risk of SNP rs965513...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1694978169

Multiple functional variants in long-range enhancer elements contribute to the risk of SNP rs965513 in thyroid cancer

About this item

Full title

Multiple functional variants in long-range enhancer elements contribute to the risk of SNP rs965513 in thyroid cancer

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2015-05, Vol.112 (19), p.6128-6133

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Significance Papillary thyroid carcinoma (PTC) displays a strong hereditary component that is, in part, due to the additive effects of numerous low-penetrance genes or variants, but virtually no mechanistic information is available. Here, we studied a well-known low-penetrance variant (SNP rs965513) located in a region devoid of coding genes. We sh...

Alternative Titles

Full title

Multiple functional variants in long-range enhancer elements contribute to the risk of SNP rs965513 in thyroid cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1694978169

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1694978169

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1506255112

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