Progesterone receptor modulates ERα action in breast cancer
Progesterone receptor modulates ERα action in breast cancer
About this item
Full title
Author / Creator
Mohammed, Hisham , Russell, I. Alasdair , Stark, Rory , Rueda, Oscar M. , Hickey, Theresa E. , Tarulli, Gerard A. , Serandour, Aurelien A. , Birrell, Stephen N. , Bruna, Alejandra , Saadi, Amel , Menon, Suraj , Hadfield, James , Pugh, Michelle , Raj, Ganesh V. , Brown, Gordon D. , D’Santos, Clive , Robinson, Jessica L. L. , Silva, Grace , Launchbury, Rosalind , Perou, Charles M. , Stingl, John , Caldas, Carlos , Tilley, Wayne D. and Carroll, Jason S.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Progesterone receptor (PR) expression is used as a biomarker of oestrogen receptor-α (ERα) function and breast cancer prognosis. Here we show that PR is not merely an ERα-induced gene target, but is also an ERα-associated protein that modulates its behaviour. In the presence of agonist ligands, PR associates with ERα to direct ERα chromatin binding...
Alternative Titles
Full title
Progesterone receptor modulates ERα action in breast cancer
Authors, Artists and Contributors
Author / Creator
Russell, I. Alasdair
Stark, Rory
Rueda, Oscar M.
Hickey, Theresa E.
Tarulli, Gerard A.
Serandour, Aurelien A.
Birrell, Stephen N.
Bruna, Alejandra
Saadi, Amel
Menon, Suraj
Hadfield, James
Pugh, Michelle
Raj, Ganesh V.
Brown, Gordon D.
D’Santos, Clive
Robinson, Jessica L. L.
Silva, Grace
Launchbury, Rosalind
Perou, Charles M.
Stingl, John
Caldas, Carlos
Tilley, Wayne D.
Carroll, Jason S.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1697215303
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1697215303
Other Identifiers
ISSN
0028-0836,1476-4687
E-ISSN
1476-4687
DOI
10.1038/nature14583
