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The conformational states of talin autoinhibition complex and its activation under forces

The conformational states of talin autoinhibition complex and its activation under forces

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1697216258

The conformational states of talin autoinhibition complex and its activation under forces

About this item

Full title

The conformational states of talin autoinhibition complex and its activation under forces

Publisher

Beijing: Science China Press

Journal title

Science China. Life sciences, 2015-07, Vol.58 (7), p.694-703

Language

English

Formats

Publication information

Publisher

Beijing: Science China Press

More information

Scope and Contents

Contents

Talin is an integrin-binding protein located at focal adhesion site and serves as both an adapter and a force transmitter. Its in- tegrin binding activity is regulated by the intramolecular autoinhibition interaction between its F3 and RS domains. Here, we used atomic force microscopy to measure the strength of talin autoinhibition complex. Our res...

Alternative Titles

Full title

The conformational states of talin autoinhibition complex and its activation under forces

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1697216258

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1697216258

Other Identifiers

ISSN

1674-7305

E-ISSN

1869-1889

DOI

10.1007/s11427-015-4873-9

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