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TIMP-1 resistant matrix metalloproteinase-9 is the predominant serum active isoform associated with...

TIMP-1 resistant matrix metalloproteinase-9 is the predominant serum active isoform associated with...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1698966787

TIMP-1 resistant matrix metalloproteinase-9 is the predominant serum active isoform associated with MRI activity in patients with multiple sclerosis

About this item

Full title

TIMP-1 resistant matrix metalloproteinase-9 is the predominant serum active isoform associated with MRI activity in patients with multiple sclerosis

Publisher

London, England: SAGE Publications

Journal title

Multiple sclerosis, 2015-08, Vol.21 (9), p.1121-1130

Language

English

Formats

Publication information

Publisher

London, England: SAGE Publications

More information

Scope and Contents

Contents

Background:
The activity of matrix metalloproteinase-9 (MMP-9) depends on two isoforms, an 82 kDa active MMP-9 modulated by its specific tissue inhibitor (TIMP-1), and a 65 kDa TIMP-1 resistant active MMP-9. The relevance of these two enzymatic isoforms in multiple sclerosis (MS) is still unknown.
Objective:
To investigate the contribution...

Alternative Titles

Full title

TIMP-1 resistant matrix metalloproteinase-9 is the predominant serum active isoform associated with MRI activity in patients with multiple sclerosis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1698966787

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1698966787

Other Identifiers

ISSN

1352-4585

E-ISSN

1477-0970

DOI

10.1177/1352458514560925

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