Vasopressin and disruption of calcium signalling in polycystic kidney disease
Vasopressin and disruption of calcium signalling in polycystic kidney disease
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London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Key Points
Polycystin-1 and polycystin-2 in the primary cilia and endoplasmic reticulum regulate intracellular calcium signalling; mutations in these proteins cause autosomal dominant polycystic kidney disease (ADPKD)
In ADPKD, reduced intracellular calcium increases the generation of and inhibits the destruction of cAMP, and reduces the rele...
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Full title
Vasopressin and disruption of calcium signalling in polycystic kidney disease
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TN_cdi_proquest_miscellaneous_1699494056
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1699494056
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ISSN
1759-5061
E-ISSN
1759-507X
DOI
10.1038/nrneph.2015.39
