An MTCH2 pathway repressing mitochondria metabolism regulates haematopoietic stem cell fate
An MTCH2 pathway repressing mitochondria metabolism regulates haematopoietic stem cell fate
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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The metabolic state of stem cells is emerging as an important determinant of their fate. In the bone marrow, haematopoietic stem cell (HSC) entry into cycle, triggered by an increase in intracellular reactive oxygen species (ROS), corresponds to a critical metabolic switch from glycolysis to mitochondrial oxidative phosphorylation (OXPHOS). Here we...
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Full title
An MTCH2 pathway repressing mitochondria metabolism regulates haematopoietic stem cell fate
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TN_cdi_proquest_miscellaneous_1700331688
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1700331688
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms8901
