T-cell exhaustion, co-stimulation and clinical outcome in autoimmunity and infection
T-cell exhaustion, co-stimulation and clinical outcome in autoimmunity and infection
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
CD8 T-cell exhaustion, although a negative prognostic indicator during persistent infections, is shown to be associated with a good outcome in autoimmune and inflammatory diseases.
T-cell exhaustion a plus in autoimmunity
CD8 T-cell exhaustion occurs in chronic viral infections, which inhibits the immune response and facilitates viral persist...
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Full title
T-cell exhaustion, co-stimulation and clinical outcome in autoimmunity and infection
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TN_cdi_proquest_miscellaneous_1700683240
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1700683240
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature14468
