Reduction of global 5-hydroxymethylcytosine is a poor prognostic factor in breast cancer patients, e...
Reduction of global 5-hydroxymethylcytosine is a poor prognostic factor in breast cancer patients, especially for an ER/PR-negative subtype
About this item
Full title
Author / Creator
Publisher
New York: Springer US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Springer US
Subjects
More information
Scope and Contents
Contents
DNA methylation at the 5 position of cytosine (5mC) is an epigenetic hallmark in cancer. The 5mC can be converted to 5-hydroxymethylcytosine (5hmC) through a ten-eleven-translocation (TET). We investigated the impact of 5mC, 5hmC, TET1, and TET2 on tumorigenesis and prognosis of breast cancer. Immunohistochemistry was used to assess the levels of 5...
Alternative Titles
Full title
Reduction of global 5-hydroxymethylcytosine is a poor prognostic factor in breast cancer patients, especially for an ER/PR-negative subtype
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1704355493
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1704355493
Other Identifiers
ISSN
0167-6806
E-ISSN
1573-7217
DOI
10.1007/s10549-015-3525-x
