MUCOSAL IMMUNOLOGY. Individual intestinal symbionts induce a distinct population of RORγ⁺ regulatory...
MUCOSAL IMMUNOLOGY. Individual intestinal symbionts induce a distinct population of RORγ⁺ regulatory T cells
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Sefik, Esen , Geva-Zatorsky, Naama , Oh, Sungwhan , Konnikova, Liza , Zemmour, David , McGuire, Abigail Manson , Burzyn, Dalia , Ortiz-Lopez, Adriana , Lobera, Mercedes , Yang, Jianfei , Ghosh, Shomir , Earl, Ashlee , Snapper, Scott B , Jupp, Ray , Kasper, Dennis , Mathis, Diane and Benoist, Christophe
Publisher
United States
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English
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Publisher
United States
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Contents
T regulatory cells that express the transcription factor Foxp3 (Foxp3(+) T(regs)) promote tissue homeostasis in several settings. We now report that symbiotic members of the human gut microbiota induce a distinct T(reg) population in the mouse colon, which constrains immuno-inflammatory responses. This induction—which we find to map to a broad, but...
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MUCOSAL IMMUNOLOGY. Individual intestinal symbionts induce a distinct population of RORγ⁺ regulatory T cells
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TN_cdi_proquest_miscellaneous_1708161280
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1708161280
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ISSN
1095-9203
E-ISSN
1095-9203
DOI
10.1126/science.aaa9420
