The Cyclophilin A–CD147 complex promotes the proliferation and homing of multiple myeloma cells
The Cyclophilin A–CD147 complex promotes the proliferation and homing of multiple myeloma cells
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Author / Creator
Zhu, Di , Wang, Zhongqiu , Zhao, Jian-Jun , Calimeri, Teresa , Meng, Jiang , Hideshima, Teru , Fulciniti, Mariateresa , Kang, Yue , Ficarro, Scott B , Tai, Yu-Tzu , Hunter, Zachary , McMilin, Douglas , Tong, Haoxuan , Mitsiades, Constantine S , Wu, Catherine J , Treon, Steven P , Dorfman, David M , Pinkus, Geraldine , Munshi, Nikhil C , Tassone, Pierfrancesco , Marto, Jarrod A , Anderson, Kenneth C and Carrasco, Ruben D
Publisher
New York: Nature Publishing Group US
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Language
English
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Publication information
Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
Cyclophilin A, secreted by bone marrow endothelial cells, acts as a chemotactic factor for myeloma cells, which helps explain their homing to the bone marrow and suggests a potential new therapeutic strategy.
B cell malignancies frequently colonize the bone marrow. The mechanisms responsible for this preferential homing are incompletely understo...
Alternative Titles
Full title
The Cyclophilin A–CD147 complex promotes the proliferation and homing of multiple myeloma cells
Authors, Artists and Contributors
Author / Creator
Wang, Zhongqiu
Zhao, Jian-Jun
Calimeri, Teresa
Meng, Jiang
Hideshima, Teru
Fulciniti, Mariateresa
Kang, Yue
Ficarro, Scott B
Tai, Yu-Tzu
Hunter, Zachary
McMilin, Douglas
Tong, Haoxuan
Mitsiades, Constantine S
Wu, Catherine J
Treon, Steven P
Dorfman, David M
Pinkus, Geraldine
Munshi, Nikhil C
Tassone, Pierfrancesco
Marto, Jarrod A
Anderson, Kenneth C
Carrasco, Ruben D
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1709178781
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1709178781
Other Identifiers
ISSN
1078-8956,1546-170X
E-ISSN
1546-170X
DOI
10.1038/nm.3867
