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BRAF-mutated clear cell sarcoma is sensitive to vemurafenib treatment

BRAF-mutated clear cell sarcoma is sensitive to vemurafenib treatment

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1713529785

BRAF-mutated clear cell sarcoma is sensitive to vemurafenib treatment

About this item

Full title

BRAF-mutated clear cell sarcoma is sensitive to vemurafenib treatment

Publisher

New York: Springer US

Journal title

Investigational new drugs, 2015-10, Vol.33 (5), p.1136-1143

Language

English

Formats

Publication information

Publisher

New York: Springer US

More information

Scope and Contents

Contents

Summary
We report a patient with a metastatic relapse of clear cell sarcoma, whose tumor harbored
BRAF
V600E mutation. Standard chemotherapy with doxorubicin and ifosfamide failed to slow the disease progression. Subsequent administration of vemurafenib (960 mg twice a day) resulted in complete tumor response after 8 weeks of treatment. Li...

Alternative Titles

Full title

BRAF-mutated clear cell sarcoma is sensitive to vemurafenib treatment

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1713529785

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1713529785

Other Identifiers

ISSN

0167-6997

E-ISSN

1573-0646

DOI

10.1007/s10637-015-0280-0

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