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Comparative analysis of oligonucleotide primers for high-throughput screening of genes encoding aden...

Comparative analysis of oligonucleotide primers for high-throughput screening of genes encoding aden...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1722188049

Comparative analysis of oligonucleotide primers for high-throughput screening of genes encoding adenylation domains of nonribosomal peptide synthetases in actinomycetes

About this item

Full title

Comparative analysis of oligonucleotide primers for high-throughput screening of genes encoding adenylation domains of nonribosomal peptide synthetases in actinomycetes

Publisher

Cham: Springer International Publishing

Journal title

Antonie van Leeuwenhoek, 2015-11, Vol.108 (5), p.1267-1274

Language

English

Formats

Publication information

Publisher

Cham: Springer International Publishing

More information

Scope and Contents

Contents

In the biosynthesis of diverse natural bioactive products the adenylation domains (ADs) of nonribosomal peptide synthetases select specific precursors from the cellular pool and activate them for further incorporation into the scaffold of the final compound. Therefore, the drug discovery programs employing PCR-based screening studies of microbial c...

Alternative Titles

Full title

Comparative analysis of oligonucleotide primers for high-throughput screening of genes encoding adenylation domains of nonribosomal peptide synthetases in actinomycetes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1722188049

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1722188049

Other Identifiers

ISSN

0003-6072

E-ISSN

1572-9699

DOI

10.1007/s10482-015-0557-5

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