Efficacy of short-term monotherapy with maraviroc, a new CCR5 antagonist, in patients infected with...
Efficacy of short-term monotherapy with maraviroc, a new CCR5 antagonist, in patients infected with HIV-1
About this item
Full title
Author / Creator
Fätkenheuer, Gerd , Pozniak, Anton L , Johnson, Margaret A , Plettenberg, Andreas , Staszewski, Schlomo , Hoepelman, Andy I M , Saag, Michael S , Goebel, Frank D , Rockstroh, Jürgen K , Dezube, Bruce J , Jenkins, Tim M , Medhurst, Christine , Sullivan, John F , Ridgway, Caroline , Abel, Samantha , James, Ian T , Youle, Mike and van der Ryst, Elna
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
We assessed the efficacy and safety of 10-d monotherapy with the orally administered CCR5 antagonist maraviroc in 63 HIV-1-positive individuals prescreened for the absence of CXCR4-using virus. Maximum reduction in viral load occurred at a median of 10–15 d, with a mean reduction of ≥1.6 log
10
copies/ml at all twice daily doses ≥100 mg. Thes...
Alternative Titles
Full title
Efficacy of short-term monotherapy with maraviroc, a new CCR5 antagonist, in patients infected with HIV-1
Authors, Artists and Contributors
Author / Creator
Pozniak, Anton L
Johnson, Margaret A
Plettenberg, Andreas
Staszewski, Schlomo
Hoepelman, Andy I M
Saag, Michael S
Goebel, Frank D
Rockstroh, Jürgen K
Dezube, Bruce J
Jenkins, Tim M
Medhurst, Christine
Sullivan, John F
Ridgway, Caroline
Abel, Samantha
James, Ian T
Youle, Mike
van der Ryst, Elna
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_17239959
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_17239959
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/nm1319
