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Dynamic m(6)A mRNA methylation directs translational control of heat shock response

Dynamic m(6)A mRNA methylation directs translational control of heat shock response

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1727436174

Dynamic m(6)A mRNA methylation directs translational control of heat shock response

About this item

Full title

Dynamic m(6)A mRNA methylation directs translational control of heat shock response

Publisher

England

Journal title

Nature (London), 2015-10, Vol.526 (7574), p.591-594

Language

English

Formats

Publication information

Publisher

England

More information

Scope and Contents

Contents

The most abundant mRNA post-transcriptional modification is N(6)-methyladenosine (m(6)A), which has broad roles in RNA biology. In mammalian cells, the asymmetric distribution of m(6)A along mRNAs results in relatively less methylation in the 5' untranslated region (5'UTR) compared to other regions. However, whether and how 5'UTR methylation is reg...

Alternative Titles

Full title

Dynamic m(6)A mRNA methylation directs translational control of heat shock response

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1727436174

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1727436174

Other Identifiers

E-ISSN

1476-4687

DOI

10.1038/nature15377

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