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Caenorhabditis elegans ALG-1 antimorphic mutations uncover functions for Argonaute in microRNA guide...

Caenorhabditis elegans ALG-1 antimorphic mutations uncover functions for Argonaute in microRNA guide...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1727691176

Caenorhabditis elegans ALG-1 antimorphic mutations uncover functions for Argonaute in microRNA guide strand selection and passenger strand disposal

About this item

Full title

Caenorhabditis elegans ALG-1 antimorphic mutations uncover functions for Argonaute in microRNA guide strand selection and passenger strand disposal

Publisher

United States: National Acad Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2015-09, Vol.112 (38), p.E5271-E5280

Language

English

Formats

Publication information

Publisher

United States: National Acad Sciences

More information

Scope and Contents

Contents

MicroRNAs are regulators of gene expression whose functions are critical for normal development and physiology. We have previously characterized mutations in a Caenorhabditis elegans microRNA-specific Argonaute ALG-1 (Argonaute-like gene) that are antimorphic [alg-1(anti)]. alg-1(anti) mutants have dramatically stronger microRNA-related phenotypes...

Alternative Titles

Full title

Caenorhabditis elegans ALG-1 antimorphic mutations uncover functions for Argonaute in microRNA guide strand selection and passenger strand disposal

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1727691176

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1727691176

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1506576112

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