Engraftment of Human Glioblastoma Cells in Immunocompetent Rats through Acquired Immunosuppression:...
Engraftment of Human Glioblastoma Cells in Immunocompetent Rats through Acquired Immunosuppression: e0136089
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Full title
Engraftment of Human Glioblastoma Cells in Immunocompetent Rats through Acquired Immunosuppression: e0136089
Author / Creator
Journal title
PloS one, 2015-08, Vol.10 (8)
Language
English
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Contents
Transplantation of glioblastoma patient biopsy spheroids to the brain of T cell-compromised Rowett (nude) rats has been established as a representative animal model for human GBMs, with a tumor take rate close to 100%. In immunocompetent littermates however, primary human GBM tissue is invariably rejected. Here we show that after repeated passaging...
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Full title
Engraftment of Human Glioblastoma Cells in Immunocompetent Rats through Acquired Immunosuppression: e0136089
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Record Identifier
TN_cdi_proquest_miscellaneous_1727693152
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1727693152
Other Identifiers
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0136089
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