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Redox distress and genetic defects conspire in systemic autoinflammatory diseases

Redox distress and genetic defects conspire in systemic autoinflammatory diseases

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1728671630

Redox distress and genetic defects conspire in systemic autoinflammatory diseases

About this item

Full title

Redox distress and genetic defects conspire in systemic autoinflammatory diseases

Publisher

London: Nature Publishing Group UK

Journal title

Nature reviews. Rheumatology, 2015-11, Vol.11 (11), p.670-680

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Key Points
Despite several advances, the pathogenesis of systemic autoinflammatory diseases (SAIDs) is only partially understood, and how mutations in causative genes lead to increased IL-1β secretion is unclear in many of these conditions
Circulating monocytes from patients with SAIDs are in a state of stress, possibly owing to the presence...

Alternative Titles

Full title

Redox distress and genetic defects conspire in systemic autoinflammatory diseases

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1728671630

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1728671630

Other Identifiers

ISSN

1759-4790

E-ISSN

1759-4804

DOI

10.1038/nrrheum.2015.105

How to access this item