Holothurian glycosaminoglycan inhibits metastasis via inhibition of P-selectin in B16F10 melanoma ce...
Holothurian glycosaminoglycan inhibits metastasis via inhibition of P-selectin in B16F10 melanoma cells
About this item
Full title
Author / Creator
Yue, Zhiqiang , Wang, Aiyun , Zhu, Zhijie , Tao, Li , Li, Yao , Zhou, Liang , Chen, Wenxing and Lu, Yin
Publisher
New York: Springer US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Springer US
Subjects
More information
Scope and Contents
Contents
P-selectin-mediated tumor cell adhesion to platelets is a well-established stage in the process of tumor metastasis. Through computerized structural analysis, we found a marine-derived polysaccharide, holothurian glycosaminoglycan (hGAG), behaved as a ligand-competitive inhibitor of P-selectin, indicating its potential to disrupt the binding of P-s...
Alternative Titles
Full title
Holothurian glycosaminoglycan inhibits metastasis via inhibition of P-selectin in B16F10 melanoma cells
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1729352736
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1729352736
Other Identifiers
ISSN
0300-8177
E-ISSN
1573-4919
DOI
10.1007/s11010-015-2546-4
