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Acute Activation of Maxi-K Channels (hSlo) by Estradiol Binding to the β Subunit

Acute Activation of Maxi-K Channels (hSlo) by Estradiol Binding to the β Subunit

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_17318995

Acute Activation of Maxi-K Channels (hSlo) by Estradiol Binding to the β Subunit

About this item

Full title

Acute Activation of Maxi-K Channels (hSlo) by Estradiol Binding to the β Subunit

Publisher

Washington, DC: American Society for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 1999-09, Vol.285 (5435), p.1929-1931

Language

English

Formats

Publication information

Publisher

Washington, DC: American Society for the Advancement of Science

More information

Scope and Contents

Contents

Maxi-K channels consist of a pore-forming α subunit and a regulatory β subunit, which confers the channel with a higher Ca$^{2+}$ sensitivity. Estradiol bound to the β subunit and activated the Maxi-K channel (hSlo) only when both α and β subunits were present. This activation was independent of the generation of intracellular signals and could be...

Alternative Titles

Full title

Acute Activation of Maxi-K Channels (hSlo) by Estradiol Binding to the β Subunit

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_17318995

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_17318995

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.285.5435.1929

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