Association of a polymorphism of the transforming growth factor- beta 1 gene with cerebral amyloid a...
Association of a polymorphism of the transforming growth factor- beta 1 gene with cerebral amyloid angiopathy
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Author / Creator
Hamaguchi, T , Okino, S , Sodeyama, N , Itoh, Y , Takahashi, A , Otomo, E , Matsushita, M , Mizusawa, H and Yamada, M
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English
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BACKGROUND: A recent study showed that transforming growth factor- beta 1 (TGF- beta 1) induces amyloid- beta deposition in cerebral blood vessels and meninges of a transgenic mouse model of Alzheimer's disease (AD), and that TGF- beta 1 mRNA levels are correlated with cerebral amyloid angiopathy (CAA) in human AD brains. A T/C polymorphism at codo...
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Full title
Association of a polymorphism of the transforming growth factor- beta 1 gene with cerebral amyloid angiopathy
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TN_cdi_proquest_miscellaneous_17328738
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_17328738
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ISSN
0022-3050
E-ISSN
1468-330X
DOI
10.1136/jnnp.2003.034454
