K33-linked polyubiquitination of Zap70 by Nrdp1 controls CD8+ T cell activation
K33-linked polyubiquitination of Zap70 by Nrdp1 controls CD8+ T cell activation
About this item
Full title
Author / Creator
Yang, Mingjin , Chen, Taoyong , Li, Xuelian , Yu, Zhou , Tang, Songqing , Wang, Chen , Gu, Yan , Liu, Yanfang , Xu, Sheng , Li, Weihua , Zhang, Xuemin , Wang, Jianli and Cao, Xuetao
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
The molecular details of the control of TCR signaling are still being determined. Cao and colleagues report that the E3 ligase Nrdp1 negatively regulates activity of the signaling kinase Zap70 selectively in CD8
+
T cells.
The key molecular mechanisms that control signaling via T cell antigen receptors (TCRs) remain to be fully elucidated....
Alternative Titles
Full title
K33-linked polyubiquitination of Zap70 by Nrdp1 controls CD8+ T cell activation
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1735335273
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1735335273
Other Identifiers
ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/ni.3258
