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Multiple, Targeted Deficiencies in Selectins Reveal a Predominant Role for P-Selectin in Leukocyte R...

Multiple, Targeted Deficiencies in Selectins Reveal a Predominant Role for P-Selectin in Leukocyte R...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_17404400

Multiple, Targeted Deficiencies in Selectins Reveal a Predominant Role for P-Selectin in Leukocyte Recruitment

About this item

Full title

Multiple, Targeted Deficiencies in Selectins Reveal a Predominant Role for P-Selectin in Leukocyte Recruitment

Publisher

United States: National Academy of Sciences of the United States of America

Journal title

Proceedings of the National Academy of Sciences - PNAS, 1999-09, Vol.96 (20), p.11452-11457

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences of the United States of America

More information

Scope and Contents

Contents

We extend our previous analyses of mice deficient in selectins by describing the generation and comparative phenotype of mice lacking one, two, or three selectins after sequential ablation of the murine genes encoding P-, E-, and L-selectins. All mice deficient in selectins are viable and fertile as homozygotes. However, mice missing both P- and E-...

Alternative Titles

Full title

Multiple, Targeted Deficiencies in Selectins Reveal a Predominant Role for P-Selectin in Leukocyte Recruitment

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_17404400

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_17404400

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.96.20.11452

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