Regulation of Nuclear Translocation of Forkhead Transcription Factor AFX by Protein Kinase B
Regulation of Nuclear Translocation of Forkhead Transcription Factor AFX by Protein Kinase B
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United States: National Academy of Sciences of the United States of America
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English
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United States: National Academy of Sciences of the United States of America
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The regulation of intracellular localization of AFX, a human Forkhead transcription factor, was studied. AFX was recovered as a phosphoprotein from transfected COS-7 cells growing in the presence of FBS, and the phosphorylation was eliminated by wortmannin, a potent inhibitor of phosphatidylinositol (PI) 3-kinase. AFX was phosphorylated in vitro by...
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Regulation of Nuclear Translocation of Forkhead Transcription Factor AFX by Protein Kinase B
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TN_cdi_proquest_miscellaneous_17409947
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_17409947
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.96.21.11836