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Regulation of Nuclear Translocation of Forkhead Transcription Factor AFX by Protein Kinase B

Regulation of Nuclear Translocation of Forkhead Transcription Factor AFX by Protein Kinase B

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_17409947

Regulation of Nuclear Translocation of Forkhead Transcription Factor AFX by Protein Kinase B

About this item

Full title

Regulation of Nuclear Translocation of Forkhead Transcription Factor AFX by Protein Kinase B

Publisher

United States: National Academy of Sciences of the United States of America

Journal title

Proceedings of the National Academy of Sciences - PNAS, 1999-10, Vol.96 (21), p.11836-11841

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences of the United States of America

More information

Scope and Contents

Contents

The regulation of intracellular localization of AFX, a human Forkhead transcription factor, was studied. AFX was recovered as a phosphoprotein from transfected COS-7 cells growing in the presence of FBS, and the phosphorylation was eliminated by wortmannin, a potent inhibitor of phosphatidylinositol (PI) 3-kinase. AFX was phosphorylated in vitro by...

Alternative Titles

Full title

Regulation of Nuclear Translocation of Forkhead Transcription Factor AFX by Protein Kinase B

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_17409947

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_17409947

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.96.21.11836

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