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Implication of mitochondria-derived reactive oxygen species, cytochrome C and caspase-3 in N-(4-Hydr...

Implication of mitochondria-derived reactive oxygen species, cytochrome C and caspase-3 in N-(4-Hydr...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_17419014

Implication of mitochondria-derived reactive oxygen species, cytochrome C and caspase-3 in N-(4-Hydroxyphenyl)retinamide-induced apoptosis in cervical carcinoma cells

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Full title

Implication of mitochondria-derived reactive oxygen species, cytochrome C and caspase-3 in N-(4-Hydroxyphenyl)retinamide-induced apoptosis in cervical carcinoma cells

Publisher

Basingstoke: Nature Publishing

Journal title

Oncogene, 1999-11, Vol.18 (46), p.6380-6387

Language

English

Formats

Publication information

Publisher

Basingstoke: Nature Publishing

Subjects

Subjects and topics

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Scope and Contents

Contents

N-(4-Hydroxyphenyl)retinamide (4HPR) is currently used in cancer prevention and therapy trials. It is thought that its effects result from induction of apoptosis. 4HPR-induced apoptosis in human cervical carcinoma C33A cells involves enhanced generation of reactive oxygen species (ROS). In this study we explored the mechanism by which 4HPR increase...

Alternative Titles

Full title

Implication of mitochondria-derived reactive oxygen species, cytochrome C and caspase-3 in N-(4-Hydroxyphenyl)retinamide-induced apoptosis in cervical carcinoma cells

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Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_17419014

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_17419014

Other Identifiers

ISSN

0950-9232

E-ISSN

1476-5594

DOI

10.1038/sj.onc.1203024

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