Highly Efficient Electro-Gene Therapy of Solid Tumor by Using an Expression Plasmid for the Herpes S...
Highly Efficient Electro-Gene Therapy of Solid Tumor by Using an Expression Plasmid for the Herpes Simplex Virus Thymidine Kinase Gene
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United States: National Academy of Sciences of the United States of America
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Language
English
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United States: National Academy of Sciences of the United States of America
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We report successful electro-gene therapy (EGT) by using plasmid DNA for tumor-bearing mice. Subcutaneously inoculated CT26 tumor was subjected to EGT, which consists of intratumoral injection of a naked plasmid encoding a marker gene or a therapeutic gene, followed by in vivo electroporation (EP). When this treatment modality is carried out with t...
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Full title
Highly Efficient Electro-Gene Therapy of Solid Tumor by Using an Expression Plasmid for the Herpes Simplex Virus Thymidine Kinase Gene
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TN_cdi_proquest_miscellaneous_17438971
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_17438971
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.97.1.354
