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Nociceptive-specific activation of ERK in spinal neurons contributes to pain hypersensitivity

Nociceptive-specific activation of ERK in spinal neurons contributes to pain hypersensitivity

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_17458324

Nociceptive-specific activation of ERK in spinal neurons contributes to pain hypersensitivity

About this item

Full title

Nociceptive-specific activation of ERK in spinal neurons contributes to pain hypersensitivity

Publisher

New York: Nature Publishing Group US

Journal title

Nature neuroscience, 1999-12, Vol.2 (12), p.1114-1119

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

We investigated the involvement of extracellular signal-regulated protein kinases (ERK) within spinal neurons in producing pain hypersensitivity. Within a minute of an intense noxious peripheral or C-fiber electrical stimulus, many phosphoERK-positive neurons were observed, most predominantly in lamina I and IIo of the ipsilateral dorsal horn. This...

Alternative Titles

Full title

Nociceptive-specific activation of ERK in spinal neurons contributes to pain hypersensitivity

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_17458324

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_17458324

Other Identifiers

ISSN

1097-6256

E-ISSN

1546-1726

DOI

10.1038/16040

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