Safety and immunogenicity of Ebola virus and Marburg virus glycoprotein DNA vaccines assessed separa...
Safety and immunogenicity of Ebola virus and Marburg virus glycoprotein DNA vaccines assessed separately and concomitantly in healthy Ugandan adults: a phase 1b, randomised, double-blind, placebo-controlled clinical trial
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Author / Creator
the RV 247 Study Team , RV 247 Study Team , Kibuuka, Hannah, MMed , Berkowitz, Nina M, MPH , Millard, Monica, MPH , Enama, Mary E, MA , Tindikahwa, Allan, MPH , Sekiziyivu, Arthur B, MSc , Costner, Pamela, BSN , Sitar, Sandra, MS , Glover, Deline, BS , Hu, Zonghui, PhD , Joshi, Gyan, MPH , Stanley, Daphne, MS , Kunchai, Meghan, MPH , Eller, Leigh Anne, PhD , Bailer, Robert T, PhD , Koup, Richard A, MD , Nabel, Gary J, MD , Mascola, John R, MD , Sullivan, Nancy J, PhD , Graham, Barney S, MD , Roederer, Mario, PhD , Michael, Nelson L, MD , Robb, Merlin L, MD and Ledgerwood, Julie E, Dr
Publisher
England: Elsevier Ltd
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Language
English
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Publisher
England: Elsevier Ltd
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Scope and Contents
Contents
Summary Background Ebola virus and Marburg virus cause serious disease outbreaks with high case fatality rates. We aimed to assess the safety and immunogenicity of two investigational DNA vaccines, one (EBO vaccine) encoding Ebola virus Zaire and Sudan glycoproteins and one (MAR) encoding Marburg virus glycoprotein. Methods RV 247 was a phase 1b, d...
Alternative Titles
Full title
Safety and immunogenicity of Ebola virus and Marburg virus glycoprotein DNA vaccines assessed separately and concomitantly in healthy Ugandan adults: a phase 1b, randomised, double-blind, placebo-controlled clinical trial
Authors, Artists and Contributors
Author / Creator
RV 247 Study Team
Kibuuka, Hannah, MMed
Berkowitz, Nina M, MPH
Millard, Monica, MPH
Enama, Mary E, MA
Tindikahwa, Allan, MPH
Sekiziyivu, Arthur B, MSc
Costner, Pamela, BSN
Sitar, Sandra, MS
Glover, Deline, BS
Hu, Zonghui, PhD
Joshi, Gyan, MPH
Stanley, Daphne, MS
Kunchai, Meghan, MPH
Eller, Leigh Anne, PhD
Bailer, Robert T, PhD
Koup, Richard A, MD
Nabel, Gary J, MD
Mascola, John R, MD
Sullivan, Nancy J, PhD
Graham, Barney S, MD
Roederer, Mario, PhD
Michael, Nelson L, MD
Robb, Merlin L, MD
Ledgerwood, Julie E, Dr
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1746889035
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1746889035
Other Identifiers
ISSN
0140-6736
E-ISSN
1474-547X
DOI
10.1016/S0140-6736(14)62385-0
