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Identification of hemoglobin variants by top-down mass spectrometry using selected diagnostic produc...

Identification of hemoglobin variants by top-down mass spectrometry using selected diagnostic produc...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1746893184

Identification of hemoglobin variants by top-down mass spectrometry using selected diagnostic product ions

About this item

Full title

Identification of hemoglobin variants by top-down mass spectrometry using selected diagnostic product ions

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Analytical and bioanalytical chemistry, 2015-04, Vol.407 (10), p.2837-2845

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Hemoglobin disorder diagnosis is a complex procedure combining several analytical steps. Due to the lack of specificity of the currently used protein analysis methods, the identification of uncommon hemoglobin variants (proteoforms) can become a hard task to accomplish. The aim of this work was to develop a mass spectrometry-based approach to quick...

Alternative Titles

Full title

Identification of hemoglobin variants by top-down mass spectrometry using selected diagnostic product ions

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1746893184

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1746893184

Other Identifiers

ISSN

1618-2642

E-ISSN

1618-2650

DOI

10.1007/s00216-015-8525-5

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