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Tyrosinase-related protein 2 as a mediator of melanoma specific resistance to cis-diamminedichloropl...

Tyrosinase-related protein 2 as a mediator of melanoma specific resistance to cis-diamminedichloropl...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_17474255

Tyrosinase-related protein 2 as a mediator of melanoma specific resistance to cis-diamminedichloroplatinum(II): therapeutic implications

About this item

Full title

Tyrosinase-related protein 2 as a mediator of melanoma specific resistance to cis-diamminedichloroplatinum(II): therapeutic implications

Publisher

Basingstoke: Nature Publishing

Journal title

Oncogene, 2000-01, Vol.19 (3), p.395-402

Language

English

Formats

Publication information

Publisher

Basingstoke: Nature Publishing

More information

Scope and Contents

Contents

A major obstacle in the systemic treatment of advanced malignant melanoma is its intrinsic resistance to conventionally used chemotherapeutic agents. In order to investigate the mechanisms of this intrinsic resistance, we have previously utilized retroviral insertional mutagenesis on an early-stage, drug sensitive human melanoma cell line (WM35) to...

Alternative Titles

Full title

Tyrosinase-related protein 2 as a mediator of melanoma specific resistance to cis-diamminedichloroplatinum(II): therapeutic implications

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_17474255

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_17474255

Other Identifiers

ISSN

0950-9232

E-ISSN

1476-5594

DOI

10.1038/sj.onc.1203315

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