Translational profiling identifies a cascade of damage initiated in motor neurons and spreading to g...
Translational profiling identifies a cascade of damage initiated in motor neurons and spreading to glia in mutant SOD1-mediated ALS
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Contents
Ubiquitous expression of amyotrophic lateral sclerosis (ALS)-causing mutations in superoxide dismutase 1 (SOD1) provokes noncell autonomous paralytic disease. By combining ribosome affinity purification and high-throughput sequencing, a cascade of mutant SOD1-dependent, cell type-specific changes are now identified. Initial mutant-dependent damage...
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Full title
Translational profiling identifies a cascade of damage initiated in motor neurons and spreading to glia in mutant SOD1-mediated ALS
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TN_cdi_proquest_miscellaneous_1749999150
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1749999150
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1520639112
