Severe B cell hyperplasia and autoimmune disease in TALL-1 transgenic mice
Severe B cell hyperplasia and autoimmune disease in TALL-1 transgenic mice
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Author / Creator
Khare, S D , Sarosi, I , Xia, X , McCabe, S , Miner, K , Solovyev, I , Hawkins, N , Kelley, M , Chang, D , Van, G , Ross, L , Delaney, J , Wang, L , Lacey, D , Boyle, W J and Hsu, Hailing
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Language
English
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Contents
TALL-1/Blys/BAFF is a member of the tumor necrosis factor (TNF) ligand superfamily that is functionally involved in B cell proliferation. Here, we describe B cell hyperplasia and autoimmune lupus-like changes in transgenic mice expressing TALL-1 under the control of a beta -actin promoter. The TALL-1 transgenic mice showed severe enlargement of spl...
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Full title
Severe B cell hyperplasia and autoimmune disease in TALL-1 transgenic mice
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Record Identifier
TN_cdi_proquest_miscellaneous_17502986
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_17502986
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ISSN
0027-8424
DOI
10.1073/pnas.050580697
